variational Bayes for variable selection
Xichen Huang, Jin Wang and Feng Liang have recently arXived a paper where they rely on variational Bayes in conjunction with a spike-and-slab prior modelling. This actually stems from an earlier paper by Carbonetto and Stephens (2012), the difference being in the implementation of the method, which is less Gibbs-like for the current paper. The approach is not fully Bayesian in that, not only an approximate (variational) representation is used for the parameters of interest (regression coefficient and presence-absence indicators) but also the nuisance parameters are replaced with MAPs. The variational approximation on the regression parameters is an independent product of spike-and-slab distributions. The authors show the approximate approach is consistent in both frequentist and Bayesian terms (under identifiability assumptions). The method is undoubtedly faster than MCMC since it shares many features with EM but I still wonder at the Bayesian interpretability of the outcome, which writes out as a product of estimated spike-and-slab mixtures. First, the weights in the mixtures are estimated by EM, hence fixed. Second, the fact that the variational approximation is a product is confusing in that the posterior distribution on the regression coefficients is unlikely to produce posterior independence.