Archive for mutation

Haldane’s short autobiography

Posted in Books, pictures, Statistics with tags , , , , , , , , , , , , , , , , , , , , , , , , on October 15, 2020 by xi'an

“I was born at Oxford, England, in 1892.  My father was Prof. J.S. Haldane, the physiologist.  I was educated at Eton and New College, Oxford.  I learned much of my science by apprenticeship, assisting my father from the age of eight onwards, and my university degree is in for classics, not science.  I was in a British infantry battalion from 1914 to 1919, and was twice wounded.  I began scientific research in 1910, and became a Fellow of New College, Oxford, in 1919.  I was at Cambridge from 1922-1932 as Reader in Biochemistry, and have been a professor in London University since 1933.  I was visiting professor in the University of Berkeley, Cal., in 1932.  In the same year I was elected a Fellow of the Royal Society of London.

My scientific work has been varied.  In the field of human physiology I am best known for my work on the effects of taking large amounts of ammonium chloride and other salts.  This has had some application in treating lead and radium poisoning.  In the field of genetics I was the first to discover linkage in mammals, to map a human chromosome, and (with Penrose) to measure the mutation rate of a human gene.  I have also made some minor discoveries in mathematics.

Whilst I may have been a credit to my universities, I have been a trial in other ways.  I was dismissed from Cambridge University in 1926 in connexion with a divorce case, but regained my post on appeal to a higher tribunal, which found that the university authorities had decided to dismiss me without hearing my case.  At present I have refused to evacuate University College, London, and, with two assistants am its sole academic occupant.  I am carrying on research there under difficulties.

Besides strictly scientific books I have written a number of popular works including a book of children’s stories.  I consider that a scientist, if he can do so, should help to render science intelligible to ordinary people, and have done my best to popularize it.

Till 1933 I tried to keep out of politics, but the support given by the British Government to Hitler and Mussolini forced me to enter the political field.  In 1936-1938 I spent three months in Republican Spain, first as an adviser on gas protection, and then as an observer of air raid precautions.  I was in the front line during fighting, and in several air raids behind the line.  Since then I have tried, with complete lack of success, to induce the British Government to adopt air raid protection measures which had proved their efficacy in Spain.

Mr. Chamberlain’s policy, and the recent developments in physics and biology, combined to convince me of the truth of the Marxist philosophy.  Though I am a member of no political party, I have of late years supported the communist party on a number of issues.  At present I am engaged on research in genetics, & research intended to save the lives of members of the British armed forces, and writing and public speaking designed to prevent the spreading of the present war, and if possible to bring about peace.  I am a fairly competent public speaker.

It will be seen that my life has been a full one.  I have been married for 14 years, measure 73 inches, weigh 245 pounds, and enjoy swimming and mountain walking.  I am bald and blue-eyed, a moderate drinker and a heavy smoker. I can read 11 languages and make public speeches in three, but am unmusical.”

J.B.S. Haldane, circa 1940

“Scientists find genetic mutation that makes woman feel no pain”

Posted in Statistics with tags , , , , , , , on March 29, 2019 by xi'an

A frontpage title in The Guardian of yesterday led me to think this was yet another entry about the Brexit Mayhem. Explaining much of the current mess. After checking it appeared to be unrelated… although the patient’s name being Cameron makes one still wonder.